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Inflammation
- Chronic gastritis (PH 1410) (pp. 38-42)
(Be able to identify this slide as gastritis and differentiate between this slide and slides showing normal stomach.)
Compare the slide with the diagram of normal stomach mucosa. Notice that on the slide, the mucosa is thinned and flattened and there is exudate (clear spaces with pink structureless material) present within the submucosa. Notice also that the lymph nodes are greatly enlarged and there are large numbers of white blood cells (stained blue) within the submucosa.   

Normal stomach  (40X2.8)                                                              Gastritis (40X2.8) 
  
Mucosa is dark red layer on upper surface and                      Mucosa is dark layer on upper surface and lining
lining pit-like vertical glands. Submucosa is                            pit-like glands. The glands are widely separated 
granular material between glands.                                             by the exudate-filled submucosa. Large lymph node
                                                                                                         at base of submucosa is surrounded by WBCs.

Normal stomach (100X2.8)                                                             
Gastritis (400X2.8)                                    
  
Mucosa is dark layer on upper surface and                              Mucosa is dark layer on upper surface and lining
lining pit-like vertical glands. Submucosa is                             pit-like glands. The glands are widely separated 
scattered cells in clear gel between glands                               by the exudate-filled submucosa, which contains.
                                                                                                          many small dark inflammatory cells (WBCs).
* What is meant by gastritis?

* Which of the 5 cardinal signs of inflammation is shown?

* What has attracted the lymphocytes into this area?

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8
Copyright 2001 - Augustine G. DiGiovanna - All rights reserved.

This material may not be reproduced or distributed in any form or by any means, or stored in any data base or retrieval system without prior written permission is obtained from Augustine G. DiGiovanna, Ph.D.,  Professor of Biology, Salisbury University, Salisbury, MD  21801.